Organic compounds including carbohydrates, amino acids, and lipids have a large diversity (and a much/less variation) in the stable isotopic composition for H, C, N, O, S, which is cased by isotopic discrimination due to the isotope effect and branched flux on ‘key’ biochemical processes in biosynthetic (or anabolic) and metabolic (or catabolic) pathways in organisms. An identification or assignment of ‘key process’ in these pathways is indispensable for better understanding of the isotopic composition and/or discrimination found in organisms, as well as of the accuracy and precision on the isotope evidence in application studies.
We would love to contribute to the understanding in-depth the complex biogeochemical processes in our planet, by using the following studies
- Illustration of 'energetic ecology' in biogeochemical cycyles;
- Illumination of ‘key process’ responsible for controlling molecular and stable isotopic compositions of organic compounds in organisms’ physiology; and
- Assessment of ‘universality' based on accurate understanding of 'generality and predictable fluctuation’ or ‘homogeneity vs. heterogeneity’ in the change of molecular and isotopic compositions with respect to the ‘key process’ in biosphere.
To do that, we love/enjoy the challenges for developing new analytical methods of (or new methodologies using) compound-specific or position-specific isotope analysis of organic compounds in natural samples.